PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8273590-5 1993 Isoproterenol (beta-agonist), rolipram (a PDE-IV inhibitor), and IBMX (a nonselective PDE inhibitor), significantly inhibited TNF-alpha but not IL-1 beta in the LPS model while having no effect in the zymosan model. 1-Methyl-3-isobutylxanthine 65-69 interleukin 1 beta Homo sapiens 144-153