PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8228625-2 1993 A dramatic reduction in CCP-1 and CCP-2 gene expression and near absence of cytolytic activity was shown to occur in these cultures when the expression of IL-2 was inhibited by 10(-6) M cyclosporin A (CsA). Cyclosporine 201-204 granzyme B Mus musculus 24-29 8228625-5 1993 The expression of CCP-1 and CCP-2 gene products and the induction of MHC-unrestricted cytotoxic activity in anti-CD3-stimulated T cell cultures therefore occur independently of IL-2 synthesis but are regulated by a CsA-sensitive mechanism. Cyclosporine 215-218 granzyme B Mus musculus 18-23