PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8142647-0 1994 Interleukin-3 and granulocyte-macrophage colony-stimulating factor induce activation of the MAPKAP kinase 2 resulting in in vitro serine phosphorylation of the small heat shock protein (Hsp 27). Serine 130-136 MAPK activated protein kinase 2 Homo sapiens 92-107 8142647-4 1994 We show here that IL-3 and GM-CSF induce MAPKAP kinase 2 activity in the human megakaryoblastic leukemia cell line MO7 and phosphorylate the human small heat shock protein Hsp 27 on serine residues in vitro. Serine 182-188 MAPK activated protein kinase 2 Homo sapiens 41-56 8142647-8 1994 Taken together, our findings indicate that tyrosine phosphorylation of MAP kinase is a prerequisite for serine phosphorylation of Hsp 27, which is mediated by MAPKAP kinase 2. Serine 104-110 MAPK activated protein kinase 2 Homo sapiens 159-174