PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8082573-7 1994 Considering the selective prerequisites for oxidative attack by cytochrome P-450 at vulnerable nitrogen centers, many cytotoxic amines belonging to the category of relatively rigid, planar molecules undergo N-oxidative activation by the cytochrome P-450IA subfamily, while more bulky amines with flexible conformation are N-oxygenated preferentially by phenobarbital-inducible cytochromes P-450. Phenobarbital 353-366 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 64-80