PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8042983-0 1994 Phosphatidylinositol 3,4,5-trisphosphate is formed from phosphatidylinositol 4,5-bisphosphate in thrombin-stimulated platelets. phosphatidylinositol 3,4,5-triphosphate 0-40 coagulation factor II, thrombin Homo sapiens 97-105 8042983-1 1994 Platelets accumulate PtdIns(3,4,5)P3 and PtdIns(3,4)P2 in response to thrombin and thrombin-receptor-directed peptide in a GTP-dependent manner. phosphatidylinositol 3,4,5-triphosphate 21-36 coagulation factor II, thrombin Homo sapiens 70-78 8042983-1 1994 Platelets accumulate PtdIns(3,4,5)P3 and PtdIns(3,4)P2 in response to thrombin and thrombin-receptor-directed peptide in a GTP-dependent manner. phosphatidylinositol 3,4,5-triphosphate 21-36 coagulation factor II, thrombin Homo sapiens 83-91 8042983-3 1994 We have examined the metabolic route by which PtdIns(3,4,5)P3 and PtdIns(3,4)P2 are synthesized by briefly (10 min) incubating platelets with high activities of [32P]Pi, followed by 20 or 60 s exposure to thrombin, and analysing the relative radioactivities of the individual phosphate groups in the resulting labelled PtdIns(3,4,5)P3 and PtdIns(3,4)P2. phosphatidylinositol 3,4,5-triphosphate 46-61 coagulation factor II, thrombin Homo sapiens 205-213