PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7981013-0	1994	Diazepam metabolism by human liver microsomes is mediated by both S-mephenytoin hydroxylase and CYP3A isoforms.	Diazepam	0-8	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	96-101	
7981013-2	1994	The primary metabolism of diazepam was studied in human liver microsomes in order to investigate the kinetics and to identify the cytochrome P450 (CYP) isoforms responsible for the formation of the main diazepam metabolites, temazepam and N-desmethyldiazepam.	Diazepam	26-34	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	130-145	
7981013-2	1994	The primary metabolism of diazepam was studied in human liver microsomes in order to investigate the kinetics and to identify the cytochrome P450 (CYP) isoforms responsible for the formation of the main diazepam metabolites, temazepam and N-desmethyldiazepam.	Diazepam	26-34	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	147-150	
7981013-2	1994	The primary metabolism of diazepam was studied in human liver microsomes in order to investigate the kinetics and to identify the cytochrome P450 (CYP) isoforms responsible for the formation of the main diazepam metabolites, temazepam and N-desmethyldiazepam.	Diazepam	203-211	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	130-145	
7981013-2	1994	The primary metabolism of diazepam was studied in human liver microsomes in order to investigate the kinetics and to identify the cytochrome P450 (CYP) isoforms responsible for the formation of the main diazepam metabolites, temazepam and N-desmethyldiazepam.	Diazepam	203-211	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	147-150	
7981013-2	1994	The primary metabolism of diazepam was studied in human liver microsomes in order to investigate the kinetics and to identify the cytochrome P450 (CYP) isoforms responsible for the formation of the main diazepam metabolites, temazepam and N-desmethyldiazepam.	Temazepam	225-234	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	130-145	
7981013-2	1994	The primary metabolism of diazepam was studied in human liver microsomes in order to investigate the kinetics and to identify the cytochrome P450 (CYP) isoforms responsible for the formation of the main diazepam metabolites, temazepam and N-desmethyldiazepam.	Temazepam	225-234	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	147-150	
7981013-2	1994	The primary metabolism of diazepam was studied in human liver microsomes in order to investigate the kinetics and to identify the cytochrome P450 (CYP) isoforms responsible for the formation of the main diazepam metabolites, temazepam and N-desmethyldiazepam.	Nordazepam	239-258	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	130-145	
7981013-2	1994	The primary metabolism of diazepam was studied in human liver microsomes in order to investigate the kinetics and to identify the cytochrome P450 (CYP) isoforms responsible for the formation of the main diazepam metabolites, temazepam and N-desmethyldiazepam.	Nordazepam	239-258	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	147-150	
7981013-11	1994	Studies with a series of CYP isoform selective inhibitors and with an inhibitory anti-CYP2C antibody indicated that temazepam formation was carried out mainly by CYP3A isoforms, whereas the formation of N-desmethyldiazepam was mediated by both CYP3A isoforms and S-mephenytoin hydroxylase.	Temazepam	116-125	cytochrome P450 family 4 subfamily F member 3	Homo sapiens	25-28	
7981013-11	1994	Studies with a series of CYP isoform selective inhibitors and with an inhibitory anti-CYP2C antibody indicated that temazepam formation was carried out mainly by CYP3A isoforms, whereas the formation of N-desmethyldiazepam was mediated by both CYP3A isoforms and S-mephenytoin hydroxylase.	Temazepam	116-125	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	86-91	
7981013-11	1994	Studies with a series of CYP isoform selective inhibitors and with an inhibitory anti-CYP2C antibody indicated that temazepam formation was carried out mainly by CYP3A isoforms, whereas the formation of N-desmethyldiazepam was mediated by both CYP3A isoforms and S-mephenytoin hydroxylase.	Temazepam	116-125	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	162-167	
7981013-11	1994	Studies with a series of CYP isoform selective inhibitors and with an inhibitory anti-CYP2C antibody indicated that temazepam formation was carried out mainly by CYP3A isoforms, whereas the formation of N-desmethyldiazepam was mediated by both CYP3A isoforms and S-mephenytoin hydroxylase.	Temazepam	116-125	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	244-249	
7981013-11	1994	Studies with a series of CYP isoform selective inhibitors and with an inhibitory anti-CYP2C antibody indicated that temazepam formation was carried out mainly by CYP3A isoforms, whereas the formation of N-desmethyldiazepam was mediated by both CYP3A isoforms and S-mephenytoin hydroxylase.	Nordazepam	203-222	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	86-91	
7981013-11	1994	Studies with a series of CYP isoform selective inhibitors and with an inhibitory anti-CYP2C antibody indicated that temazepam formation was carried out mainly by CYP3A isoforms, whereas the formation of N-desmethyldiazepam was mediated by both CYP3A isoforms and S-mephenytoin hydroxylase.	Nordazepam	203-222	cytochrome P450 family 3 subfamily A member 4	Homo sapiens	244-249