PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7864660-3 1994 Our aim was to assess the effects of sensitizing metal haptens (nickel, cobalt and chromium) compared with the toxic metal cadmium on the induction of ICAM-1 and the production of TNF alpha by epidermal cells. Nickel 64-70 intercellular adhesion molecule 1 Homo sapiens 151-157 7864660-5 1994 Using FACS analysis, ICAM-1 expression was found to be induced only by nickel. Nickel 71-77 intercellular adhesion molecule 1 Homo sapiens 21-27 7864660-10 1994 These results indicate that the metals studied are able to induce an aggressive cellular effect, and that nickel, by its ICAM-1 induction, may play a major role in the keratinocyte activation state during allergic contact dermatitis. Nickel 106-112 intercellular adhesion molecule 1 Homo sapiens 121-127