PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7851398-0 1995 Inhibition of 3-hydroxy-3-methylglutaryl-CoA reductase and citrate synthase by sulfoxides and sulfones of substrate-analogue CoA-thioether derivatives. Sulfones 94-102 citrate synthase Homo sapiens 59-75 7851398-3 1995 Sulfoxides and sulfones of substrate analogues of citrate synthase were also prepared. Sulfones 15-23 citrate synthase Homo sapiens 50-66 7851398-4 1995 When tested in the appropriate reaction with citrate synthase, the sulfoxide and sulfone derivatives were competitive inhibitors, but their Ki values were greater than the Km values of the corresponding unmodified substrates. Sulfones 81-88 citrate synthase Homo sapiens 45-61