PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7751024-3 1995 Stimulation of non-IL-4-treated cells with ionomycin (10 microM) for periods of 30 min to 8 hr induced expression of mRNA encoding IL-3, IL-4 and IL-8 but was without effect on levels of mRNA for tumour necrosis factor (TNF)-alpha or beta-actin. Ionomycin 43-52 interleukin 3 Homo sapiens 131-135 7751024-5 1995 More notably, the IL-4 treatment produced a pronounced elevation of mRNA for IL-3 and IL-8 when the cells were subsequently activated with ionomycin. Ionomycin 139-148 interleukin 3 Homo sapiens 77-81 7751024-7 1995 Quantitation of cDNA by competitive polymerase chain reaction (PCR) revealed that the IL-4 treatment produced a sixfold increase in ionomycin-induced levels of cellular IL-3 mRNA, a fourfold increase in induced IL-8 mRNA and less than a twofold increase in induced IL-4 mRNA. Ionomycin 132-141 interleukin 3 Homo sapiens 169-173 7751024-8 1995 The IL-4 treatment led to a 15- to 20-fold increase in ionomycin-induced secretion of IL-3 product and a doubling of induced IL-8 product. Ionomycin 55-64 interleukin 3 Homo sapiens 86-90