PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7750577-3 1995 We now show that one of these compounds (SB 203580) inhibits RK in vitro (IC50 = 0.6 microM), suppresses the activation of MAPKAP kinase-2 and prevents the phosphorylation of heat shock protein (HSP) 27 in response to interleukin-1, cellular stresses and bacterial endotoxin in vivo. SB 203580 41-50 heat shock protein family B (small) member 1 Homo sapiens 175-202