PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7720667-3 1995 AR-positive human prostate cancer cells, LNCaP, were incubated with either the calcium ionophore A23187 or the intracellular endoplasmic reticulum Ca(2+)-ATPase inhibitor thapsigargin. Calcimycin 97-103 androgen receptor Homo sapiens 0-2 7720667-5 1995 Both A23187 and thapsigargin were found to down-regulate steady state AR mRNA levels in a time- and dose-dependent manner. Calcimycin 5-11 androgen receptor Homo sapiens 70-72 7720667-6 1995 AR mRNA began to decrease after 6-8 h of incubation with 10(-6) M A23187 or 10(-7) M thapsigargin, reaching a nadir at 16 and 10 h of incubation, respectively. Calcimycin 66-72 androgen receptor Homo sapiens 0-2 7720667-8 1995 AR protein levels were found to be decreased after 12 h of incubation with either 10(-6) M A23187 or 10(-7) M thapsigargin. Calcimycin 91-97 androgen receptor Homo sapiens 0-2