PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7704341-4 1995 The results of numerical simulation show that: the addition of drugs that inhibit neuronal uptake and catechol-O-methyltransferase cause the augmentation of noradrenaline action on post-synaptic structures and an increase in the amplitude of the generated inhibitory post-synaptic potential (IPSP); treatment with adrenergic antagonists reduces the amplitude of IPSP; decrease in the concentration of extracellular Ca2+ ions and application of TTX abolish the post-synaptic response. Norepinephrine 157-170 catechol-O-methyltransferase Homo sapiens 102-130