PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7688545-0	1993	Bradykinin inhibits cyclic AMP accumulation in D384-human astrocytoma cells via a calcium-dependent inhibition of adenylyl cyclase.	Cyclic AMP	20-30	kininogen 1	Homo sapiens	0-10	
7688545-1	1993	Bradykinin causes a concentration-dependent, transient rise in intracellular Ca2+ and a sustained inhibition of forskolin-, dopamine- and 5"-N-ethyl-carboxamidoadenosine (NECA)-stimulated cAMP accumulation in D384 astrocytoma cells.	Cyclic AMP	188-192	kininogen 1	Homo sapiens	0-10	
7688545-2	1993	Chelation of intracellular calcium abolished bradykinin"s inhibitory effect on cAMP accumulation.	Cyclic AMP	79-83	kininogen 1	Homo sapiens	45-55	
7688545-9	1993	Bradykinin treatment, which attenuates cAMP accumulation in intact cells, did not do so in plasma membranes.	Cyclic AMP	39-43	kininogen 1	Homo sapiens	0-10	
7688545-10	1993	These findings suggest that bradykinin-induced inhibition of cAMP formation in D384 cells requires mobilization of [Ca2+]i and subsequent entry of Ca2+ which directly interacts with a component of the adenylyl cyclase system.	Cyclic AMP	61-65	kininogen 1	Homo sapiens	28-38