PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7650005-7 1995 However, histamine treatment inhibited Raf-1 but not MAP kinase activation following treatment with either platelet-derived growth factor or epidermal growth factor, implying a Raf-1-independent MAP kinase activation pathway. Histamine 9-18 RAF1 Bos taurus 39-44 7650005-7 1995 However, histamine treatment inhibited Raf-1 but not MAP kinase activation following treatment with either platelet-derived growth factor or epidermal growth factor, implying a Raf-1-independent MAP kinase activation pathway. Histamine 9-18 RAF1 Bos taurus 177-182 7650005-8 1995 In summary, our data suggest a model whereby 5-HT activates MAP kinase via a protein kinase C/Raf-1 pathway, and histamine attenuates MAP kinase activation by serotonin via activation of cAMP-dependent protein kinase A and inhibition of Raf-1. Histamine 113-122 RAF1 Bos taurus 237-242