PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7602106-0	1995	Thapsigargin and cyclopiazonic acid initiate rapid and dramatic increases of IL-6 mRNA expression and IL-6 secretion in murine peritoneal macrophages.	cyclopiazonic acid	17-35	interleukin 6	Mus musculus	77-81	
7602106-0	1995	Thapsigargin and cyclopiazonic acid initiate rapid and dramatic increases of IL-6 mRNA expression and IL-6 secretion in murine peritoneal macrophages.	cyclopiazonic acid	17-35	interleukin 6	Mus musculus	102-106	
7602106-3	1995	The activity of these inhibitors was linked to an important biologic response, because both cyclopiazonic acid and thapsigargin induced rapid and dramatic increases in IL-6 mRNA expression and secretion.	cyclopiazonic acid	92-110	interleukin 6	Mus musculus	168-172	
7602106-5	1995	The increased mRNA expression was coupled to translation and secretion of this monokine since cyclopiazonic acid and thapsigargin induced significant increases in IL-6 secretion as early as 2 h, and up to approximately 70-fold increases by 20 h, when compared with control cultures.	cyclopiazonic acid	94-112	interleukin 6	Mus musculus	163-167	
7602106-6	1995	Taken together, these results demonstrate that both cyclopiazonic acid and thapsigargin generate potent intracellular signals that initiate rapid and dramatic production of IL-6.	cyclopiazonic acid	52-70	interleukin 6	Mus musculus	173-177	
7602106-7	1995	Both thapsigargin and cyclopiazonic acid increased IL-6 mRNA expression at 15 min in the absence of Ca2+ influx from the extracellular medium.	cyclopiazonic acid	22-40	interleukin 6	Mus musculus	51-55