PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7592869-1	1995	FK506, an immunosuppressant that prolongs allograft survival, is a co-drug with its intracellular receptor, FKBP12.	Tacrolimus	0-5	FKBP prolyl isomerase 1A pseudogene 1	Homo sapiens	108-114	
7592869-2	1995	The FKBP12.FK506 complex inhibits calcineurin, a critical signaling molecule during T-cell activation.	Tacrolimus	11-16	FKBP prolyl isomerase 1A pseudogene 1	Homo sapiens	4-10	
7592869-3	1995	FKBP12 was, until recently, the sole FKBP known to mediate calcineurin inhibition at clinically relevant FK506 concentrations.	Tacrolimus	105-110	FKBP prolyl isomerase 1A pseudogene 1	Homo sapiens	0-6	
7592869-5	1995	Recently, a novel protein, FKBP12.6, was found to inhibit calcineurin at clinically relevant FK506 concentrations.	Tacrolimus	93-98	FKBP prolyl isomerase 1B	Homo sapiens	27-35	
7592869-7	1995	In transfected Jurkat cells, FKBP12.6 is equivalent to FKBP12 at mediating the inhibitory effects of FK506.	Tacrolimus	101-106	FKBP prolyl isomerase 1B	Homo sapiens	29-37	
7592869-7	1995	In transfected Jurkat cells, FKBP12.6 is equivalent to FKBP12 at mediating the inhibitory effects of FK506.	Tacrolimus	101-106	FKBP prolyl isomerase 1A pseudogene 1	Homo sapiens	29-35	
7592869-10	1995	Our results suggest that FKBP12.6 has both a unique physiological role in excitation-contraction coupling in cardiac muscle and the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin.	Tacrolimus	202-207	FKBP prolyl isomerase 1B	Homo sapiens	25-33	
7592869-10	1995	Our results suggest that FKBP12.6 has both a unique physiological role in excitation-contraction coupling in cardiac muscle and the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin.	Sirolimus	212-221	FKBP prolyl isomerase 1B	Homo sapiens	25-33