PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7574697-7	1995	Purified recombinant Cyp 2C8 and 2C10 were reconstituted in the presence of NADPH and NADPH-cytochrome P450 reductase and shown to metabolize arachidonic via olefin epoxidation with both proteins generating, almost exclusively, epoxygenase-derived products (94 and 90% of total products, respectively).	NADP	76-81	cytochrome P450 family 2 subfamily C member 8	Homo sapiens	21-37	
7574697-7	1995	Purified recombinant Cyp 2C8 and 2C10 were reconstituted in the presence of NADPH and NADPH-cytochrome P450 reductase and shown to metabolize arachidonic via olefin epoxidation with both proteins generating, almost exclusively, epoxygenase-derived products (94 and 90% of total products, respectively).	Alkenes	158-164	cytochrome P450 family 2 subfamily C member 8	Homo sapiens	21-37	
7574697-10	1995	Compared to Cyp 2C8, arachidonic acid epoxidation by Cyp 2C10 was less regio- and stereo-selective and generated mixtures of 8(S), 9(R)-, 11(S), 12(R)-, and 14(R), 15(S)-epoxyeicosatrienoic acids (with optical purities of 66, 69, 63%, respectively).	Arachidonic Acid	21-37	cytochrome P450 family 2 subfamily C member 8	Homo sapiens	12-19	
7574697-10	1995	Compared to Cyp 2C8, arachidonic acid epoxidation by Cyp 2C10 was less regio- and stereo-selective and generated mixtures of 8(S), 9(R)-, 11(S), 12(R)-, and 14(R), 15(S)-epoxyeicosatrienoic acids (with optical purities of 66, 69, 63%, respectively).	Arachidonic Acid	21-37	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	53-61	
7574697-10	1995	Compared to Cyp 2C8, arachidonic acid epoxidation by Cyp 2C10 was less regio- and stereo-selective and generated mixtures of 8(S), 9(R)-, 11(S), 12(R)-, and 14(R), 15(S)-epoxyeicosatrienoic acids (with optical purities of 66, 69, 63%, respectively).	Sulfur	126-129	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	53-61	
7574697-10	1995	Compared to Cyp 2C8, arachidonic acid epoxidation by Cyp 2C10 was less regio- and stereo-selective and generated mixtures of 8(S), 9(R)-, 11(S), 12(R)-, and 14(R), 15(S)-epoxyeicosatrienoic acids (with optical purities of 66, 69, 63%, respectively).	(r)	132-135	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	53-61	
7574697-10	1995	Compared to Cyp 2C8, arachidonic acid epoxidation by Cyp 2C10 was less regio- and stereo-selective and generated mixtures of 8(S), 9(R)-, 11(S), 12(R)-, and 14(R), 15(S)-epoxyeicosatrienoic acids (with optical purities of 66, 69, 63%, respectively).	(s)-epoxyeicosatrienoic acids	166-195	cytochrome P450 family 2 subfamily C member 9	Homo sapiens	53-61	
7574697-11	1995	Importantly, recombinant Cyp 2C8 and 2C10 epoxidized the arachidonic acid 11, 12-olefin with opposite enantiofacial selectivities.	arachidonic acid 11, 12-olefin	57-87	cytochrome P450 family 2 subfamily C member 8	Homo sapiens	25-41	
7574697-14	1995	Hence, we propose that Cyp 2C8 is one of the human cytochrome P450 isoforms responsible for the metabolism of endogenous arachidonic acid pools.	Arachidonic Acid	121-137	cytochrome P450 family 2 subfamily C member 8	Homo sapiens	23-30