PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7564270-3 1995 EXPERIMENTAL DESIGN: Cells were labeled with the fluorescent probes rhodamine-phalloidin and FITC-DNase-1 specific for F- and G-actin, respectively. Fluorescein-5-isothiocyanate 93-97 deoxyribonuclease 1 Rattus norvegicus 98-105 7564270-6 1995 RESULTS: In response to endothelin-1, 0.1 microM, vasopressin 1.0 microM, or angiotensin II 1.0 microM, mesangial cells cultured in normal glucose displayed partial disassembly of F-actin characterized by decreased fluorescence intensity (microfilament bundle pattern changed to network) with no change in G-actin fluorescence. Glucose 139-146 endothelin 1 Rattus norvegicus 24-36 7564270-9 1995 The effect of high glucose on mesangial cell actin was reversed by returning the cells to normal glucose for 2 days, stimulation with insulin 2 micrograms/ml, or with a protein kinase C inhibitor. Glucose 19-26 insulin 2 Rattus norvegicus 134-143 7564270-10 1995 Mesangial cells in high glucose were smaller in planar area and exhibited loss of contractile response to endothelin-1 (0.1 microM) or vasopressin (1.0 microM) measured by videomicroscopy. Glucose 24-31 endothelin 1 Rattus norvegicus 106-118