PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7544748-4 1995 Using a cytotoxicity assay and a radioimmunoassay, we observed significant increases in levels of tumor necrosis factor-alpha (TNF-alpha) in the colitis mucosa and detected interleukin-1 alpha in the mucosa of 3 of 5 DSS rats and an increase in TNF-alpha had a tendency to be inhibited by treatment with FK506. Tacrolimus 304-309 tumor necrosis factor Rattus norvegicus 98-125 7544748-4 1995 Using a cytotoxicity assay and a radioimmunoassay, we observed significant increases in levels of tumor necrosis factor-alpha (TNF-alpha) in the colitis mucosa and detected interleukin-1 alpha in the mucosa of 3 of 5 DSS rats and an increase in TNF-alpha had a tendency to be inhibited by treatment with FK506. Tacrolimus 304-309 tumor necrosis factor Rattus norvegicus 127-136