PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7541023-1	1995	B-cell antigen receptor (BCR)-mediated calcium response can be blocked by phenylarsine oxide (PAO), a dithiol group-reactive protein tyrosine phosphatase inhibitor.	Calcium	39-46	BCR activator of RhoGEF and GTPase	Homo sapiens	0-23	
7541023-1	1995	B-cell antigen receptor (BCR)-mediated calcium response can be blocked by phenylarsine oxide (PAO), a dithiol group-reactive protein tyrosine phosphatase inhibitor.	Calcium	39-46	BCR activator of RhoGEF and GTPase	Homo sapiens	25-28	
7541023-1	1995	B-cell antigen receptor (BCR)-mediated calcium response can be blocked by phenylarsine oxide (PAO), a dithiol group-reactive protein tyrosine phosphatase inhibitor.	oxophenylarsine	74-92	BCR activator of RhoGEF and GTPase	Homo sapiens	0-23	
7541023-1	1995	B-cell antigen receptor (BCR)-mediated calcium response can be blocked by phenylarsine oxide (PAO), a dithiol group-reactive protein tyrosine phosphatase inhibitor.	oxophenylarsine	74-92	BCR activator of RhoGEF and GTPase	Homo sapiens	25-28	
7541023-1	1995	B-cell antigen receptor (BCR)-mediated calcium response can be blocked by phenylarsine oxide (PAO), a dithiol group-reactive protein tyrosine phosphatase inhibitor.	oxophenylarsine	94-97	BCR activator of RhoGEF and GTPase	Homo sapiens	0-23	
7541023-1	1995	B-cell antigen receptor (BCR)-mediated calcium response can be blocked by phenylarsine oxide (PAO), a dithiol group-reactive protein tyrosine phosphatase inhibitor.	oxophenylarsine	94-97	BCR activator of RhoGEF and GTPase	Homo sapiens	25-28	
7541023-1	1995	B-cell antigen receptor (BCR)-mediated calcium response can be blocked by phenylarsine oxide (PAO), a dithiol group-reactive protein tyrosine phosphatase inhibitor.	dithiol	102-109	BCR activator of RhoGEF and GTPase	Homo sapiens	0-23	
7541023-1	1995	B-cell antigen receptor (BCR)-mediated calcium response can be blocked by phenylarsine oxide (PAO), a dithiol group-reactive protein tyrosine phosphatase inhibitor.	dithiol	102-109	BCR activator of RhoGEF and GTPase	Homo sapiens	25-28	
7541023-4	1995	In contrast, calcium response induced by a putative syk activator, H2O2, exhibited only a moderate sensitivity to PAO, demonstrating that PAO did not cause general suppression of all the functions leading to Ca2+ mobilization.	Calcium	13-20	spleen associated tyrosine kinase	Homo sapiens	52-55	
7541023-4	1995	In contrast, calcium response induced by a putative syk activator, H2O2, exhibited only a moderate sensitivity to PAO, demonstrating that PAO did not cause general suppression of all the functions leading to Ca2+ mobilization.	Hydrogen Peroxide	67-71	spleen associated tyrosine kinase	Homo sapiens	52-55	
7541023-4	1995	In contrast, calcium response induced by a putative syk activator, H2O2, exhibited only a moderate sensitivity to PAO, demonstrating that PAO did not cause general suppression of all the functions leading to Ca2+ mobilization.	oxophenylarsine	114-117	spleen associated tyrosine kinase	Homo sapiens	52-55	
7541023-4	1995	In contrast, calcium response induced by a putative syk activator, H2O2, exhibited only a moderate sensitivity to PAO, demonstrating that PAO did not cause general suppression of all the functions leading to Ca2+ mobilization.	oxophenylarsine	138-141	spleen associated tyrosine kinase	Homo sapiens	52-55	
7541023-6	1995	Since BCR cross-linking did not generate non-responsiveness to H2O2 in the presence of PAO, and PAO-treated cells remained responsive to syk activation by H2O2, we suppose that PAO may inhibit BCR-mediated signal transduction events upstream of syk activation.	oxophenylarsine	96-99	spleen associated tyrosine kinase	Homo sapiens	137-140	
7541023-6	1995	Since BCR cross-linking did not generate non-responsiveness to H2O2 in the presence of PAO, and PAO-treated cells remained responsive to syk activation by H2O2, we suppose that PAO may inhibit BCR-mediated signal transduction events upstream of syk activation.	oxophenylarsine	96-99	BCR activator of RhoGEF and GTPase	Homo sapiens	193-196	
7541023-6	1995	Since BCR cross-linking did not generate non-responsiveness to H2O2 in the presence of PAO, and PAO-treated cells remained responsive to syk activation by H2O2, we suppose that PAO may inhibit BCR-mediated signal transduction events upstream of syk activation.	oxophenylarsine	96-99	spleen associated tyrosine kinase	Homo sapiens	245-248	
7541023-6	1995	Since BCR cross-linking did not generate non-responsiveness to H2O2 in the presence of PAO, and PAO-treated cells remained responsive to syk activation by H2O2, we suppose that PAO may inhibit BCR-mediated signal transduction events upstream of syk activation.	Hydrogen Peroxide	155-159	spleen associated tyrosine kinase	Homo sapiens	137-140	
7541023-6	1995	Since BCR cross-linking did not generate non-responsiveness to H2O2 in the presence of PAO, and PAO-treated cells remained responsive to syk activation by H2O2, we suppose that PAO may inhibit BCR-mediated signal transduction events upstream of syk activation.	oxophenylarsine	96-99	spleen associated tyrosine kinase	Homo sapiens	137-140	
7541023-6	1995	Since BCR cross-linking did not generate non-responsiveness to H2O2 in the presence of PAO, and PAO-treated cells remained responsive to syk activation by H2O2, we suppose that PAO may inhibit BCR-mediated signal transduction events upstream of syk activation.	oxophenylarsine	96-99	BCR activator of RhoGEF and GTPase	Homo sapiens	193-196	
7541023-6	1995	Since BCR cross-linking did not generate non-responsiveness to H2O2 in the presence of PAO, and PAO-treated cells remained responsive to syk activation by H2O2, we suppose that PAO may inhibit BCR-mediated signal transduction events upstream of syk activation.	oxophenylarsine	96-99	spleen associated tyrosine kinase	Homo sapiens	245-248	
7541023-7	1995	This assumption was supported by additional data, indicating that PAO was able to modulate functions of at least 2 different protein tyrosine kinase enzymes involved in BCR-mediated signaling.	oxophenylarsine	66-69	BCR activator of RhoGEF and GTPase	Homo sapiens	169-172	
7541023-8	1995	PAO induced rapid and dose-dependent tyrosine phosphorylation of lyn and selectively inhibited BCR-mediated tyrosine phosphorylation of syk.	oxophenylarsine	0-3	LYN proto-oncogene, Src family tyrosine kinase	Homo sapiens	65-68	
7541023-8	1995	PAO induced rapid and dose-dependent tyrosine phosphorylation of lyn and selectively inhibited BCR-mediated tyrosine phosphorylation of syk.	oxophenylarsine	0-3	BCR activator of RhoGEF and GTPase	Homo sapiens	95-98	
7541023-8	1995	PAO induced rapid and dose-dependent tyrosine phosphorylation of lyn and selectively inhibited BCR-mediated tyrosine phosphorylation of syk.	oxophenylarsine	0-3	spleen associated tyrosine kinase	Homo sapiens	136-139	
7541023-8	1995	PAO induced rapid and dose-dependent tyrosine phosphorylation of lyn and selectively inhibited BCR-mediated tyrosine phosphorylation of syk.	Tyrosine	37-45	LYN proto-oncogene, Src family tyrosine kinase	Homo sapiens	65-68	
7541023-8	1995	PAO induced rapid and dose-dependent tyrosine phosphorylation of lyn and selectively inhibited BCR-mediated tyrosine phosphorylation of syk.	Tyrosine	108-116	BCR activator of RhoGEF and GTPase	Homo sapiens	95-98	
7541023-8	1995	PAO induced rapid and dose-dependent tyrosine phosphorylation of lyn and selectively inhibited BCR-mediated tyrosine phosphorylation of syk.	Tyrosine	108-116	spleen associated tyrosine kinase	Homo sapiens	136-139	
7541023-9	1995	The results presented in this paper demonstrate that PAO may provoke cellular desensitization process by alteration of the signal transducer functions of lyn and syk tyrosine kinase enzymes.	oxophenylarsine	53-56	LYN proto-oncogene, Src family tyrosine kinase	Homo sapiens	154-157	
7541023-9	1995	The results presented in this paper demonstrate that PAO may provoke cellular desensitization process by alteration of the signal transducer functions of lyn and syk tyrosine kinase enzymes.	oxophenylarsine	53-56	spleen associated tyrosine kinase	Homo sapiens	162-165