PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7532082-2	1994	We have recently found that in the presence, but not in the absence, of foetal calf serum, spermine inhibits the production of nitric oxide (NO) in cultured J774.2 macrophages stimulated with bacterial endotoxin (lipopolysaccharide; LPS) or with gamma-interferon (IFN), showing that polyamines may act as suppressants of NO-mediated immune functions.	Spermine	91-99	interferon gamma	Mus musculus	246-268	
7532082-10	1994	Thus, spermine is an inhibitor of the induction of iNOS.	Spermine	6-14	nitric oxide synthase 2, inducible	Mus musculus	51-55	
7532082-14	1994	The effect of sper mine on nitrite production can be prevented by isoniazid, hydrazine or hydroxylamine, inhibitors of spermine oxidase, as well as by phenylhydrazine, an aldehyde inhibitor.	Nitrites	27-34	spermine oxidase	Mus musculus	119-135	
7532082-15	1994	We have, therefore, tested the effects of spermine dialdehyde or malon dialdehyde on the induction of iNOS.	N,N'-bis(3-propionaldehyde)-1,4-diaminobutane	42-61	nitric oxide synthase 2, inducible	Mus musculus	102-106	
7532082-15	1994	We have, therefore, tested the effects of spermine dialdehyde or malon dialdehyde on the induction of iNOS.	Malondialdehyde	65-81	nitric oxide synthase 2, inducible	Mus musculus	102-106	
7532082-16	1994	Spermine dialdehyde (SDA, 10(-5) M) inhibits nitrite formation by IFN-activated J774.2 cells in the absence of serum when given as a pretreatment but not when given 6 h after stimulation.	N,N'-bis(3-propionaldehyde)-1,4-diaminobutane	0-19	interferon gamma	Mus musculus	66-69	
7532082-16	1994	Spermine dialdehyde (SDA, 10(-5) M) inhibits nitrite formation by IFN-activated J774.2 cells in the absence of serum when given as a pretreatment but not when given 6 h after stimulation.	N,N'-bis(3-propionaldehyde)-1,4-diaminobutane	21-24	interferon gamma	Mus musculus	66-69	
7532082-16	1994	Spermine dialdehyde (SDA, 10(-5) M) inhibits nitrite formation by IFN-activated J774.2 cells in the absence of serum when given as a pretreatment but not when given 6 h after stimulation.	Nitrites	45-52	interferon gamma	Mus musculus	66-69	
7532082-20	1994	The inhibitory effect of polyamines on iNOS induction appears to be fairly specific to iNOS, for spermine does not inhibit LPS-induced production of prostaglandin F2 alpha or tumour necrosis factor.	Polyamines	25-35	nitric oxide synthase 2, inducible	Mus musculus	39-43