PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7526844-1 1994 In cultured glomerular mesangial cells, interleukin 1 beta (IL-1 beta) has been shown to induce a dose- and time-dependent accumulation of nitrite, a stable metabolite of nitric oxide (NO). Nitrites 139-146 interleukin 1 beta Rattus norvegicus 40-58 7526844-1 1994 In cultured glomerular mesangial cells, interleukin 1 beta (IL-1 beta) has been shown to induce a dose- and time-dependent accumulation of nitrite, a stable metabolite of nitric oxide (NO). Nitrites 139-146 interleukin 1 beta Rattus norvegicus 60-69 7526844-1 1994 In cultured glomerular mesangial cells, interleukin 1 beta (IL-1 beta) has been shown to induce a dose- and time-dependent accumulation of nitrite, a stable metabolite of nitric oxide (NO). Nitric Oxide 171-183 interleukin 1 beta Rattus norvegicus 40-58 7526844-1 1994 In cultured glomerular mesangial cells, interleukin 1 beta (IL-1 beta) has been shown to induce a dose- and time-dependent accumulation of nitrite, a stable metabolite of nitric oxide (NO). Nitric Oxide 171-183 interleukin 1 beta Rattus norvegicus 60-69 7526844-3 1994 Here we report that addition of the biologically active phorbol esters, phorbol 12-myristate 13-acetate (PMA) and phorbol 12,13-dibutyrate (PDBu), dose-dependently inhibited the IL-1 beta-stimulated increase in iNOS mRNA levels and nitrite production. Phorbol Esters 56-70 interleukin 1 beta Rattus norvegicus 178-187 7526844-3 1994 Here we report that addition of the biologically active phorbol esters, phorbol 12-myristate 13-acetate (PMA) and phorbol 12,13-dibutyrate (PDBu), dose-dependently inhibited the IL-1 beta-stimulated increase in iNOS mRNA levels and nitrite production. Phorbol Esters 56-70 nitric oxide synthase 2 Rattus norvegicus 211-215 7526844-3 1994 Here we report that addition of the biologically active phorbol esters, phorbol 12-myristate 13-acetate (PMA) and phorbol 12,13-dibutyrate (PDBu), dose-dependently inhibited the IL-1 beta-stimulated increase in iNOS mRNA levels and nitrite production. Tetradecanoylphorbol Acetate 72-103 interleukin 1 beta Rattus norvegicus 178-187 7526844-3 1994 Here we report that addition of the biologically active phorbol esters, phorbol 12-myristate 13-acetate (PMA) and phorbol 12,13-dibutyrate (PDBu), dose-dependently inhibited the IL-1 beta-stimulated increase in iNOS mRNA levels and nitrite production. Tetradecanoylphorbol Acetate 72-103 nitric oxide synthase 2 Rattus norvegicus 211-215 7526844-3 1994 Here we report that addition of the biologically active phorbol esters, phorbol 12-myristate 13-acetate (PMA) and phorbol 12,13-dibutyrate (PDBu), dose-dependently inhibited the IL-1 beta-stimulated increase in iNOS mRNA levels and nitrite production. Tetradecanoylphorbol Acetate 105-108 interleukin 1 beta Rattus norvegicus 178-187 7526844-3 1994 Here we report that addition of the biologically active phorbol esters, phorbol 12-myristate 13-acetate (PMA) and phorbol 12,13-dibutyrate (PDBu), dose-dependently inhibited the IL-1 beta-stimulated increase in iNOS mRNA levels and nitrite production. Tetradecanoylphorbol Acetate 105-108 nitric oxide synthase 2 Rattus norvegicus 211-215 7526844-3 1994 Here we report that addition of the biologically active phorbol esters, phorbol 12-myristate 13-acetate (PMA) and phorbol 12,13-dibutyrate (PDBu), dose-dependently inhibited the IL-1 beta-stimulated increase in iNOS mRNA levels and nitrite production. Phorbol 12,13-Dibutyrate 114-138 interleukin 1 beta Rattus norvegicus 178-187 7526844-3 1994 Here we report that addition of the biologically active phorbol esters, phorbol 12-myristate 13-acetate (PMA) and phorbol 12,13-dibutyrate (PDBu), dose-dependently inhibited the IL-1 beta-stimulated increase in iNOS mRNA levels and nitrite production. Phorbol 12,13-Dibutyrate 114-138 nitric oxide synthase 2 Rattus norvegicus 211-215 7526844-3 1994 Here we report that addition of the biologically active phorbol esters, phorbol 12-myristate 13-acetate (PMA) and phorbol 12,13-dibutyrate (PDBu), dose-dependently inhibited the IL-1 beta-stimulated increase in iNOS mRNA levels and nitrite production. Phorbol 12,13-Dibutyrate 140-144 interleukin 1 beta Rattus norvegicus 178-187 7526844-3 1994 Here we report that addition of the biologically active phorbol esters, phorbol 12-myristate 13-acetate (PMA) and phorbol 12,13-dibutyrate (PDBu), dose-dependently inhibited the IL-1 beta-stimulated increase in iNOS mRNA levels and nitrite production. Phorbol 12,13-Dibutyrate 140-144 nitric oxide synthase 2 Rattus norvegicus 211-215 7526844-3 1994 Here we report that addition of the biologically active phorbol esters, phorbol 12-myristate 13-acetate (PMA) and phorbol 12,13-dibutyrate (PDBu), dose-dependently inhibited the IL-1 beta-stimulated increase in iNOS mRNA levels and nitrite production. Nitrites 232-239 interleukin 1 beta Rattus norvegicus 178-187 7526844-8 1994 In contrast, a 24 h treatment of mesangial cells with PMA or PDBu, a regimen that also causes depletion of PKC-epsilon, abolished inhibition of IL-1 beta-induced iNOS expression and nitrite production. Nitrites 182-189 interleukin 1 beta Rattus norvegicus 144-153