PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7525847-0 1994 IL-5 receptor-mediated tyrosine phosphorylation of SH2/SH3-containing proteins and activation of Bruton"s tyrosine and Janus 2 kinases. Tyrosine 23-31 interleukin 5 Homo sapiens 0-4 7525847-3 1994 We investigated the role of IL-5R alpha in tyrosine phosphorylation of molecules involved in IL-5 signal transduction, using an IL-5-dependent early B cell line, Y16 and transfectants expressing intact or mutant IL-5R alpha together with intact beta c. Tyrosine 43-51 interleukin 5 receptor subunit alpha Homo sapiens 28-39 7525847-3 1994 We investigated the role of IL-5R alpha in tyrosine phosphorylation of molecules involved in IL-5 signal transduction, using an IL-5-dependent early B cell line, Y16 and transfectants expressing intact or mutant IL-5R alpha together with intact beta c. Tyrosine 43-51 interleukin 5 Homo sapiens 28-32 7525847-3 1994 We investigated the role of IL-5R alpha in tyrosine phosphorylation of molecules involved in IL-5 signal transduction, using an IL-5-dependent early B cell line, Y16 and transfectants expressing intact or mutant IL-5R alpha together with intact beta c. Tyrosine 43-51 interleukin 5 Homo sapiens 93-97 7525847-5 1994 This confirms that IL-5R alpha plays a critical role in protein-tyrosine phosphorylation which triggers cell growth. Tyrosine 64-72 interleukin 5 receptor subunit alpha Homo sapiens 19-30 7525847-6 1994 IL-5 stimulation results in rapid tyrosine phosphorylation of beta c and proteins containing Src homology 2 (SH2) and/or SH3 domains such as phosphatidyl-inositol-3 kinase, Shc, Vav, and HS1, suggesting their involvement in IL-5-mediated signal transduction. Tyrosine 34-42 interleukin 5 Homo sapiens 0-4 7525847-6 1994 IL-5 stimulation results in rapid tyrosine phosphorylation of beta c and proteins containing Src homology 2 (SH2) and/or SH3 domains such as phosphatidyl-inositol-3 kinase, Shc, Vav, and HS1, suggesting their involvement in IL-5-mediated signal transduction. Tyrosine 34-42 colony stimulating factor 2 receptor subunit beta Homo sapiens 62-68 7525847-6 1994 IL-5 stimulation results in rapid tyrosine phosphorylation of beta c and proteins containing Src homology 2 (SH2) and/or SH3 domains such as phosphatidyl-inositol-3 kinase, Shc, Vav, and HS1, suggesting their involvement in IL-5-mediated signal transduction. Tyrosine 34-42 SHC adaptor protein 1 Homo sapiens 173-176 7525847-6 1994 IL-5 stimulation results in rapid tyrosine phosphorylation of beta c and proteins containing Src homology 2 (SH2) and/or SH3 domains such as phosphatidyl-inositol-3 kinase, Shc, Vav, and HS1, suggesting their involvement in IL-5-mediated signal transduction. Tyrosine 34-42 vav guanine nucleotide exchange factor 1 Homo sapiens 178-181 7525847-6 1994 IL-5 stimulation results in rapid tyrosine phosphorylation of beta c and proteins containing Src homology 2 (SH2) and/or SH3 domains such as phosphatidyl-inositol-3 kinase, Shc, Vav, and HS1, suggesting their involvement in IL-5-mediated signal transduction. Tyrosine 34-42 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta Homo sapiens 187-190 7525847-6 1994 IL-5 stimulation results in rapid tyrosine phosphorylation of beta c and proteins containing Src homology 2 (SH2) and/or SH3 domains such as phosphatidyl-inositol-3 kinase, Shc, Vav, and HS1, suggesting their involvement in IL-5-mediated signal transduction. Tyrosine 34-42 interleukin 5 Homo sapiens 224-228 7525847-7 1994 IL-5 stimulation significantly enhanced activities of Janus 2 and B cell-specific Bruton"s tyrosine kinases (JAK2 and Btk) and increased the tyrosine phosphorylation of JAK2 kinase. Tyrosine 91-99 interleukin 5 Homo sapiens 0-4 7525847-7 1994 IL-5 stimulation significantly enhanced activities of Janus 2 and B cell-specific Bruton"s tyrosine kinases (JAK2 and Btk) and increased the tyrosine phosphorylation of JAK2 kinase. Tyrosine 91-99 Janus kinase 2 Homo sapiens 109-113