PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7478679-0 1995 The development of morphine tolerance and dependence is associated with translocation of protein kinase C. Morphine 19-27 protein kinase C, gamma Rattus norvegicus 89-105 7478679-1 1995 The development of tolerance to the analgesic effects of morphine as well as morphine dependence were greatly reduced by co-administration with morphine of GM1 ganglioside, a substance reported to block the translocation of protein kinase C (PKC) from cytosol to membrane of neurons. Morphine 57-65 protein kinase C, gamma Rattus norvegicus 224-240 7478679-1 1995 The development of tolerance to the analgesic effects of morphine as well as morphine dependence were greatly reduced by co-administration with morphine of GM1 ganglioside, a substance reported to block the translocation of protein kinase C (PKC) from cytosol to membrane of neurons. Morphine 57-65 protein kinase C, gamma Rattus norvegicus 242-245 7478679-1 1995 The development of tolerance to the analgesic effects of morphine as well as morphine dependence were greatly reduced by co-administration with morphine of GM1 ganglioside, a substance reported to block the translocation of protein kinase C (PKC) from cytosol to membrane of neurons. Morphine 77-85 protein kinase C, gamma Rattus norvegicus 224-240 7478679-1 1995 The development of tolerance to the analgesic effects of morphine as well as morphine dependence were greatly reduced by co-administration with morphine of GM1 ganglioside, a substance reported to block the translocation of protein kinase C (PKC) from cytosol to membrane of neurons. Morphine 77-85 protein kinase C, gamma Rattus norvegicus 242-245 7478679-1 1995 The development of tolerance to the analgesic effects of morphine as well as morphine dependence were greatly reduced by co-administration with morphine of GM1 ganglioside, a substance reported to block the translocation of protein kinase C (PKC) from cytosol to membrane of neurons. Morphine 77-85 protein kinase C, gamma Rattus norvegicus 224-240 7478679-1 1995 The development of tolerance to the analgesic effects of morphine as well as morphine dependence were greatly reduced by co-administration with morphine of GM1 ganglioside, a substance reported to block the translocation of protein kinase C (PKC) from cytosol to membrane of neurons. Morphine 77-85 protein kinase C, gamma Rattus norvegicus 242-245 7478679-2 1995 Rats made tolerant to intrathecal administration of morphine showed increased membrane-bound PKC in the superficial layers (laminae I and II) of the spinal cord dorsal horn but not in deeper layers. Morphine 52-60 protein kinase C, gamma Rattus norvegicus 93-96