PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7451639-2 1981 In vitro, histamine (10(-5)-10(-7) M) caused a dose-related significant stimulation of immunoreactive PTH (iPTH) secretion; this was blocked by the simultaneous addition of cimetidine (10(-5) M). Histamine 10-19 parathyroid hormone Homo sapiens 102-105 7451639-7 1981 The observed inhibition of basal PTH concentration by cimetidine induced histamine H2 receptor blockade (but not by H1 blockade) in normal human subjects suggests that endogenous histamine with H2 receptor activation stimulates even basal PTH secretion and may serve as a modulator of PTH secretion in normal man. Histamine 73-82 parathyroid hormone Homo sapiens 33-36