PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7359015-2 1980 We have found that the position on the PHA dose-response curve that is studied is the most important determinant of whether cortisol inhibits 3H-thymidine incorporation into lymphocyte DNA. Tritium 142-144 lamin B receptor Homo sapiens 39-42 7359015-2 1980 We have found that the position on the PHA dose-response curve that is studied is the most important determinant of whether cortisol inhibits 3H-thymidine incorporation into lymphocyte DNA. Thymidine 145-154 lamin B receptor Homo sapiens 39-42 7359015-6 1980 When monocytes were reduced from 14% to 1.4%, cortisol (5 microM) caused a 30% reduction in thymidine incorporation in cultures stimulated by 0.6 to 1.2 microgram/ml PHA. Hydrocortisone 46-54 lamin B receptor Homo sapiens 166-169 7359015-7 1980 Much greater cortisol suppression of thymidine incorporation occurred if the concentration of PHA was reduced. Thymidine 37-46 lamin B receptor Homo sapiens 94-97 7359015-8 1980 For example, reduction of the PHA concentration from 1.2 to 0.075 microgram/ml resulted in an increase in suppression by 5 microM cortisol from 5% to 90% even in the presence of 14% monocytes. Hydrocortisone 130-138 lamin B receptor Homo sapiens 30-33 7359015-9 1980 These data indicate that the suppressive effects of glucocorticoids on blastogenesis and thymidine incorporation in vitro depend principally on the concentration of PHA used to stimulate blastogenesis and secondarily on the proportion of monocytes in the culture system. Thymidine 89-98 lamin B receptor Homo sapiens 165-168