PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 7126620-1 1982 The activity of the rate-limiting enzyme of the cholesterol biosynthetic pathway, 3-hydroxy-3-methylglutaryl coenzyme A reductase in Chinese hamster ovary (CHO) cells decreased more rapidly in cells treated with 25-hydroxycholesterol alone (t 1/2 = 1.5 h) than in those incubated with cycloheximide alone (t 1/2 = 5 h). 25-hydroxycholesterol 212-233 3-hydroxy-3-methylglutaryl-coenzyme A reductase Cricetulus griseus 82-129