PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
6239876-0	1984	Carbohydrate moiety of von Willebrand factor is not necessary for maintaining multimeric structure and ristocetin cofactor activity but protects from proteolytic degradation.	Carbohydrates	0-12	von Willebrand factor	Homo sapiens	23-44	
6239876-1	1984	To better define the role of carbohydrate in the structure and ristocetin cofactor activity of von Willebrand factor, we have removed up to 83% of total hexose by sequential treatment of the molecule with endo-beta-N-acetyl-glucosaminidase F (endo F), neuraminidase, and beta-galactosidase.	Carbohydrates	29-41	von Willebrand factor	Homo sapiens	95-116	
6239876-5	1984	All multimers of unreduced carbohydrate-modified von Willebrand factor migrated more rapidly in SDS-agarose, but the triplet pattern of individual multimers was unchanged.	Carbohydrates	27-39	von Willebrand factor	Homo sapiens	49-70	
6239876-11	1984	This suggested that carbohydrate was protecting von Willebrand factor against traces of one or more protease contaminants.	Carbohydrates	20-32	von Willebrand factor	Homo sapiens	48-69	
6239876-14	1984	In contrast, the multimeric structure of von Willebrand factor with intact carbohydrate was not affected by plasmin under similar conditions.	Carbohydrates	75-87	von Willebrand factor	Homo sapiens	41-62	
6239876-15	1984	These studies suggest that carbohydrate protects von Willebrand factor from disaggregation occurring secondarily to proteolytic attack but does not play a direct role in maintaining its multimeric structure or ristocetin cofactor activity.	Carbohydrates	27-39	von Willebrand factor	Homo sapiens	49-70