PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 4074386-1 1985 Acrolein, a highly reactive aldehyde found in cigarette smoke, was shown to induce time-dependent inactivation of NAD+-linked 15-hydroxyprostaglandin dehydrogenase from porcine lung. NAD 114-118 carbonyl reductase 1 Homo sapiens 126-163 4074386-6 1985 Inactivation of pulmonary NAD+-linked 15-hydroxyprostaglandin dehydrogenase by acrolein may alter cellular and circulating thromboxane/prostacyclin ratios and subsequently disturb vascular homeostasis and augment inflammatory and anaphylactic responses in smokers. NAD 26-29 carbonyl reductase 1 Homo sapiens 38-75