PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 4061517-1 1985 Variations in cytochrome P-450 levels may influence the responsiveness of uterine and breast tissue as well as carcinomas to endocrine therapy and may be of particular importance with agents such as tamoxifen (Nolvadex) where hydroxylation is known to alter therapeutic activities. Tamoxifen 199-208 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 14-30 4061517-1 1985 Variations in cytochrome P-450 levels may influence the responsiveness of uterine and breast tissue as well as carcinomas to endocrine therapy and may be of particular importance with agents such as tamoxifen (Nolvadex) where hydroxylation is known to alter therapeutic activities. Tamoxifen 210-218 cytochrome P450 family 4 subfamily F member 3 Homo sapiens 14-30