PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35628627-0	2022	Anti-Inflammatory Effects of Psoralen Derivatives on RAW264.7 Cells via Regulation of the NF-kappaB and MAPK Signaling Pathways.	Ficusin	29-37	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	90-99	
35628627-4	2022	In addition, xanthotoxol treatment decreased the PGE2, IL-6, and IL-1beta production caused by LPS stimulation in a concentration-dependent manner.	xanthotoxol	13-24	interleukin 6	Mus musculus	55-59	
35628627-4	2022	In addition, xanthotoxol treatment decreased the PGE2, IL-6, and IL-1beta production caused by LPS stimulation in a concentration-dependent manner.	xanthotoxol	13-24	interleukin 1 alpha	Mus musculus	65-73	
35628627-5	2022	Moreover, Western blot results showed that the protein levels of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2), which activated with LPS treatment, were decreased by xanthotoxol treatment.	xanthotoxol	188-199	nitric oxide synthase 2, inducible	Mus musculus	65-96	
35628627-5	2022	Moreover, Western blot results showed that the protein levels of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2), which activated with LPS treatment, were decreased by xanthotoxol treatment.	xanthotoxol	188-199	nitric oxide synthase 2, inducible	Mus musculus	98-102	
35628627-5	2022	Moreover, Western blot results showed that the protein levels of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2), which activated with LPS treatment, were decreased by xanthotoxol treatment.	xanthotoxol	188-199	prostaglandin-endoperoxide synthase 2	Mus musculus	108-124	
35628627-5	2022	Moreover, Western blot results showed that the protein levels of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2), which activated with LPS treatment, were decreased by xanthotoxol treatment.	xanthotoxol	188-199	prostaglandin-endoperoxide synthase 2	Mus musculus	126-131	
35628627-6	2022	Mechanistic studies revealed that xanthotoxol also suppressed LPS-stimulated phosphorylation of the inhibitor of kappaBalpha (IkappaBalpha), p38 mitogen-activated protein kinase (MAPK), and c-Jun N-terminal kinase (JNK) in RAW 264.7 cells.	xanthotoxol	34-45	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha	Mus musculus	126-138	
35628627-6	2022	Mechanistic studies revealed that xanthotoxol also suppressed LPS-stimulated phosphorylation of the inhibitor of kappaBalpha (IkappaBalpha), p38 mitogen-activated protein kinase (MAPK), and c-Jun N-terminal kinase (JNK) in RAW 264.7 cells.	xanthotoxol	34-45	mitogen-activated protein kinase 8	Mus musculus	190-213	
35628627-6	2022	Mechanistic studies revealed that xanthotoxol also suppressed LPS-stimulated phosphorylation of the inhibitor of kappaBalpha (IkappaBalpha), p38 mitogen-activated protein kinase (MAPK), and c-Jun N-terminal kinase (JNK) in RAW 264.7 cells.	xanthotoxol	34-45	mitogen-activated protein kinase 8	Mus musculus	215-218	
35628627-7	2022	The Western blot assay results show that xanthotoxol suppresses LPS-induced p65 translocation from cytosol to the nucleus in RAW 264.7 cells.	xanthotoxol	41-52	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	Mus musculus	76-79	
35628627-10	2022	These results demonstrate that xanthotoxol is a potential therapeutic agent for topical application that inhibits inflammation via the MAPK and NF-kappaB pathways.	xanthotoxol	31-42	nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105	Mus musculus	144-153