PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35590365-0 2022 Arginine regulates inflammation response-induced by Fowl Adenovirus serotype 4 via JAK2/STAT3 pathway. Arginine 0-8 Janus kinase 2 Gallus gallus 83-87 35590365-0 2022 Arginine regulates inflammation response-induced by Fowl Adenovirus serotype 4 via JAK2/STAT3 pathway. Arginine 0-8 signal transducer and activator of transcription 3 Gallus gallus 88-93 35590365-6 2022 The findings demonstrated that FAdV-4 induced inflammatory response and activated JAK2/STAT3 pathway. fadv-4 31-37 Janus kinase 2 Gallus gallus 82-86 35590365-6 2022 The findings demonstrated that FAdV-4 induced inflammatory response and activated JAK2/STAT3 pathway. fadv-4 31-37 signal transducer and activator of transcription 3 Gallus gallus 87-92 35590365-8 2022 After treatment with 1.92% arginine level diet to broilers or 300 mug/mL arginine culture medium to LMH cell line with FAdV-4 infection at the same time, we found that the mRNA levels of IL-6, IL-1beta, IFN-alpha and the protein levels of p-JAK2, p-STAT3 were down-regulated, compared with FAdV-4 infection group. Arginine 27-35 interleukin 6 Gallus gallus 187-191 35590365-8 2022 After treatment with 1.92% arginine level diet to broilers or 300 mug/mL arginine culture medium to LMH cell line with FAdV-4 infection at the same time, we found that the mRNA levels of IL-6, IL-1beta, IFN-alpha and the protein levels of p-JAK2, p-STAT3 were down-regulated, compared with FAdV-4 infection group. Arginine 73-81 interleukin 6 Gallus gallus 187-191 35590365-8 2022 After treatment with 1.92% arginine level diet to broilers or 300 mug/mL arginine culture medium to LMH cell line with FAdV-4 infection at the same time, we found that the mRNA levels of IL-6, IL-1beta, IFN-alpha and the protein levels of p-JAK2, p-STAT3 were down-regulated, compared with FAdV-4 infection group. Arginine 73-81 interleukin 1, beta Gallus gallus 193-201 35590365-8 2022 After treatment with 1.92% arginine level diet to broilers or 300 mug/mL arginine culture medium to LMH cell line with FAdV-4 infection at the same time, we found that the mRNA levels of IL-6, IL-1beta, IFN-alpha and the protein levels of p-JAK2, p-STAT3 were down-regulated, compared with FAdV-4 infection group. Arginine 73-81 interferon Gallus gallus 203-212 35590365-8 2022 After treatment with 1.92% arginine level diet to broilers or 300 mug/mL arginine culture medium to LMH cell line with FAdV-4 infection at the same time, we found that the mRNA levels of IL-6, IL-1beta, IFN-alpha and the protein levels of p-JAK2, p-STAT3 were down-regulated, compared with FAdV-4 infection group. Arginine 73-81 Janus kinase 2 Gallus gallus 241-245 35590365-8 2022 After treatment with 1.92% arginine level diet to broilers or 300 mug/mL arginine culture medium to LMH cell line with FAdV-4 infection at the same time, we found that the mRNA levels of IL-6, IL-1beta, IFN-alpha and the protein levels of p-JAK2, p-STAT3 were down-regulated, compared with FAdV-4 infection group. Arginine 73-81 signal transducer and activator of transcription 3 Gallus gallus 249-254 35590365-9 2022 Furthermore, we confirmed that the inflammation induced by FAdV-4 was ameliorated by pre-treatment with JAK inhibitor AG490 in LMH cells, and it was further alleviated in LMH cells treatment with AG490 and ARG. fadv-4 59-65 Janus kinase 3 Gallus gallus 104-107 35590365-9 2022 Furthermore, we confirmed that the inflammation induced by FAdV-4 was ameliorated by pre-treatment with JAK inhibitor AG490 in LMH cells, and it was further alleviated in LMH cells treatment with AG490 and ARG. alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide 118-123 Janus kinase 3 Gallus gallus 104-107 35590365-10 2022 CONCLUSIONS: These above results provide new insight that arginine protects hepatocytes against inflammation induced by FAdV-4 through JAK2/STAT3 signaling pathway. Arginine 58-66 Janus kinase 2 Gallus gallus 135-139 35590365-10 2022 CONCLUSIONS: These above results provide new insight that arginine protects hepatocytes against inflammation induced by FAdV-4 through JAK2/STAT3 signaling pathway. Arginine 58-66 signal transducer and activator of transcription 3 Gallus gallus 140-145 35590365-10 2022 CONCLUSIONS: These above results provide new insight that arginine protects hepatocytes against inflammation induced by FAdV-4 through JAK2/STAT3 signaling pathway. fadv-4 120-126 Janus kinase 2 Gallus gallus 135-139 35590365-10 2022 CONCLUSIONS: These above results provide new insight that arginine protects hepatocytes against inflammation induced by FAdV-4 through JAK2/STAT3 signaling pathway. fadv-4 120-126 signal transducer and activator of transcription 3 Gallus gallus 140-145