PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35567986-0 2022 Procyanidins and its metabolites by gut microbiome improves insulin resistance in gestational diabetes mellitus mice model via regulating NF-kappaB and NLRP3 inflammasome pathway. Proanthocyanidins 0-12 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 138-147 35567986-0 2022 Procyanidins and its metabolites by gut microbiome improves insulin resistance in gestational diabetes mellitus mice model via regulating NF-kappaB and NLRP3 inflammasome pathway. Proanthocyanidins 0-12 NLR family, pyrin domain containing 3 Mus musculus 152-157 35567986-8 2022 PA inhibited inflammation by decreasing the levels of IL-6, TNF-alpha, IL-17 and CRP, which also been blocked in the IFD mice. Proanthocyanidins 0-2 interleukin 6 Mus musculus 54-58 35567986-8 2022 PA inhibited inflammation by decreasing the levels of IL-6, TNF-alpha, IL-17 and CRP, which also been blocked in the IFD mice. Proanthocyanidins 0-2 tumor necrosis factor Mus musculus 60-69 35567986-8 2022 PA inhibited inflammation by decreasing the levels of IL-6, TNF-alpha, IL-17 and CRP, which also been blocked in the IFD mice. Proanthocyanidins 0-2 interleukin 17A Mus musculus 71-76 35567986-8 2022 PA inhibited inflammation by decreasing the levels of IL-6, TNF-alpha, IL-17 and CRP, which also been blocked in the IFD mice. Proanthocyanidins 0-2 C-reactive protein, pentraxin-related Mus musculus 81-84 35567986-10 2022 Mechanistically, PA treatment suppressed the nuclear factor-kappaB (NF-kappaB) p65 nuclear translocation and nucleotide-binding domain like receptor protein 3 (NLRP3) inflammasome activation. Proanthocyanidins 17-19 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 45-66 35567986-10 2022 Mechanistically, PA treatment suppressed the nuclear factor-kappaB (NF-kappaB) p65 nuclear translocation and nucleotide-binding domain like receptor protein 3 (NLRP3) inflammasome activation. Proanthocyanidins 17-19 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 68-77 35567986-10 2022 Mechanistically, PA treatment suppressed the nuclear factor-kappaB (NF-kappaB) p65 nuclear translocation and nucleotide-binding domain like receptor protein 3 (NLRP3) inflammasome activation. Proanthocyanidins 17-19 v-rel reticuloendotheliosis viral oncogene homolog A (avian) Mus musculus 79-82 35567986-10 2022 Mechanistically, PA treatment suppressed the nuclear factor-kappaB (NF-kappaB) p65 nuclear translocation and nucleotide-binding domain like receptor protein 3 (NLRP3) inflammasome activation. Proanthocyanidins 17-19 NLR family, pyrin domain containing 3 Mus musculus 109-158 35567986-10 2022 Mechanistically, PA treatment suppressed the nuclear factor-kappaB (NF-kappaB) p65 nuclear translocation and nucleotide-binding domain like receptor protein 3 (NLRP3) inflammasome activation. Proanthocyanidins 17-19 NLR family, pyrin domain containing 3 Mus musculus 160-165 35567986-11 2022 In vitro studies, 4-hydroxyphenylacetic acid and 3-(4-hydroxyphenyl) propionic acid, main intestinal flora metabolites of PA restrained NF-kappaB/NLRP3 activation. 4-hydroxyphenylacetic acid 18-44 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 136-145 35567986-11 2022 In vitro studies, 4-hydroxyphenylacetic acid and 3-(4-hydroxyphenyl) propionic acid, main intestinal flora metabolites of PA restrained NF-kappaB/NLRP3 activation. 4-hydroxyphenylacetic acid 18-44 NLR family, pyrin domain containing 3 Mus musculus 146-151 35567986-11 2022 In vitro studies, 4-hydroxyphenylacetic acid and 3-(4-hydroxyphenyl) propionic acid, main intestinal flora metabolites of PA restrained NF-kappaB/NLRP3 activation. phloretic acid 49-83 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 136-145 35567986-11 2022 In vitro studies, 4-hydroxyphenylacetic acid and 3-(4-hydroxyphenyl) propionic acid, main intestinal flora metabolites of PA restrained NF-kappaB/NLRP3 activation. phloretic acid 49-83 NLR family, pyrin domain containing 3 Mus musculus 146-151 35567986-11 2022 In vitro studies, 4-hydroxyphenylacetic acid and 3-(4-hydroxyphenyl) propionic acid, main intestinal flora metabolites of PA restrained NF-kappaB/NLRP3 activation. Proanthocyanidins 122-124 NLR family, pyrin domain containing 3 Mus musculus 146-151 35567986-12 2022 In conclusions, PA improved IR via NF-kappaB/NLRP3 pathway in GDM and postpartum mice, which partly through its metabolites by gut microbiome. Proanthocyanidins 16-18 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus 35-44 35567986-12 2022 In conclusions, PA improved IR via NF-kappaB/NLRP3 pathway in GDM and postpartum mice, which partly through its metabolites by gut microbiome. Proanthocyanidins 16-18 NLR family, pyrin domain containing 3 Mus musculus 45-50