PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35549216-4	2022	Acylation occurred in two stages: (i) proton transfer from Ser441 to His296 concerted with the nucleophilic attack of Ser441 to the substrate"s P1-Arg and (ii) proton transfer from His296 to the P1"-Ser residue concerted with the cleavage of the ArgP1-SerP1" peptide bond, with a Gibbs activation energy of 17.1 and 15.8 kcal mol-1, relative to the reactant.	Arginine	147-150	diacylglycerol O-acyltransferase 1	Homo sapiens	246-251