PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35513212-4 2022 The highly cytotoxic ROS was continuously produced via Fe2+-mediated and TA-assisted enhanced Fenton reaction as well as Ce6-induced photosensitive reaction, and meanwhile, the intratumoral upregulated p53 expression inactivated glutathione peroxidase 4 (GPX4) to suppress lipid peroxidation (LPO) resistance, thus resulting in amplified oxidative stress and intensified ferroptosis-apoptosis therapy. Reactive Oxygen Species 21-24 tumor protein p53 Homo sapiens 202-205