PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35509834-1	2022	Dimethylarginine dimethylaminohydrolase 1 (DDAH1) protects against cerebral ischemia injury via regulating the level of asymmetric dimethylarginine (ADMA).	dimethylarginine	131-147	dimethylarginine dimethylaminohydrolase 1	Rattus norvegicus	0-41	
35509834-1	2022	Dimethylarginine dimethylaminohydrolase 1 (DDAH1) protects against cerebral ischemia injury via regulating the level of asymmetric dimethylarginine (ADMA).	dimethylarginine	131-147	dimethylarginine dimethylaminohydrolase 1	Rattus norvegicus	43-48	
35509834-1	2022	Dimethylarginine dimethylaminohydrolase 1 (DDAH1) protects against cerebral ischemia injury via regulating the level of asymmetric dimethylarginine (ADMA).	N,N-dimethylarginine	149-153	dimethylarginine dimethylaminohydrolase 1	Rattus norvegicus	0-41	
35509834-1	2022	Dimethylarginine dimethylaminohydrolase 1 (DDAH1) protects against cerebral ischemia injury via regulating the level of asymmetric dimethylarginine (ADMA).	N,N-dimethylarginine	149-153	dimethylarginine dimethylaminohydrolase 1	Rattus norvegicus	43-48	
35509834-2	2022	This study is aimed at exploring the effect of adiponectin resistance on ADMA-induced neuronal loss in ischemic stroke (IS) and the underlying mechanism.	N,N-dimethylarginine	73-77	adiponectin, C1Q and collagen domain containing	Rattus norvegicus	47-58	
35509834-4	2022	Plasma and brain adiponectin levels and the expressions of adiponectin receptor 1 (APR1), adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 (APPL1), adenosine monophosphate-activated protein kinase (AMPK), and phosphorylated AMPK were determined after 24 h, 3 days, and 7 days.	Phosphotyrosine	107-122	adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1	Rattus norvegicus	172-177	
35509834-4	2022	Plasma and brain adiponectin levels and the expressions of adiponectin receptor 1 (APR1), adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 (APPL1), adenosine monophosphate-activated protein kinase (AMPK), and phosphorylated AMPK were determined after 24 h, 3 days, and 7 days.	Phosphotyrosine	107-122	protein kinase AMP-activated catalytic subunit alpha 2	Rattus norvegicus	180-228	
35509834-4	2022	Plasma and brain adiponectin levels and the expressions of adiponectin receptor 1 (APR1), adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 (APPL1), adenosine monophosphate-activated protein kinase (AMPK), and phosphorylated AMPK were determined after 24 h, 3 days, and 7 days.	Leucine	154-161	adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1	Rattus norvegicus	172-177	
35509834-8	2022	DDAH1 was overexpressed in neurons, after which FOXO1 expression, ROS production, adiponectin resistance, and cell viability were detected.	Reactive Oxygen Species	66-69	dimethylarginine dimethylaminohydrolase 1	Rattus norvegicus	0-5	
35509834-11	2022	ROS accumulation and phosphorylated FOXO1 expression also increased with DDAH1 depletion.	Reactive Oxygen Species	0-3	dimethylarginine dimethylaminohydrolase 1	Rattus norvegicus	73-78	
35509834-12	2022	Following DDAH1 overexpression, decreased cell viability and inhibited adiponectin signaling induced by OGD/R were alleviated in primary neurons, accompanied by reduced ROS production and phosphorylated FOXO1 expression.	Reactive Oxygen Species	169-172	dimethylarginine dimethylaminohydrolase 1	Rattus norvegicus	10-15