PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35445730-0 2022 EGFR inhibition reverses epithelial-mesenchymal transition, and decreases tamoxifen resistance via Snail and Twist downregulation in breast cancer cells. Tamoxifen 74-83 epidermal growth factor receptor Homo sapiens 0-4 35445730-6 2022 In addition, it was observed that the inhibition of epidermal growth factor receptor (EGFR) reversed the EMT phenotype in tamoxifen-resistant MCF7 (MCF-7/TR) cells via the downregulation of Snail and Twist. Tamoxifen 122-131 epidermal growth factor receptor Homo sapiens 52-84 35445730-6 2022 In addition, it was observed that the inhibition of epidermal growth factor receptor (EGFR) reversed the EMT phenotype in tamoxifen-resistant MCF7 (MCF-7/TR) cells via the downregulation of Snail and Twist. Tamoxifen 122-131 epidermal growth factor receptor Homo sapiens 86-90 35445730-7 2022 Notably, the EGFR inhibitor, gefitinib, decreased tamoxifen resistance, migration and invasion through the inhibition of Snail and Twist. Tamoxifen 50-59 epidermal growth factor receptor Homo sapiens 13-17 35445730-8 2022 On the whole, the results of the present study suggest that EGFR may be a promising therapeutic target for tamoxifen-resistant breast cancer. Tamoxifen 107-116 epidermal growth factor receptor Homo sapiens 60-64