PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35438255-0 2022 Phosphoproteomics identifies pathways underlying the role of receptor-interaction protein kinase 3 in alcohol-associated liver disease and uncovers apoptosis signal-regulating kinase 1 as a target. Alcohols 102-109 receptor-interacting serine-threonine kinase 3 Mus musculus 61-98 35438255-0 2022 Phosphoproteomics identifies pathways underlying the role of receptor-interaction protein kinase 3 in alcohol-associated liver disease and uncovers apoptosis signal-regulating kinase 1 as a target. Alcohols 102-109 mitogen-activated protein kinase kinase kinase 5 Mus musculus 148-184 35438255-7 2022 Of particular importance, chronic ethanol feeding to C57BL/6 mice decreased the phosphorylation of apoptosis signal-regulating kinase 1 (ASK1) at serine (S)1036/S1040 (S1029/S1033 human), sites linked with the inhibition of ASK1 death-promoting activity. Ethanol 34-41 mitogen-activated protein kinase kinase kinase 5 Mus musculus 99-135 35438255-7 2022 Of particular importance, chronic ethanol feeding to C57BL/6 mice decreased the phosphorylation of apoptosis signal-regulating kinase 1 (ASK1) at serine (S)1036/S1040 (S1029/S1033 human), sites linked with the inhibition of ASK1 death-promoting activity. Ethanol 34-41 mitogen-activated protein kinase kinase kinase 5 Mus musculus 137-141 35438255-7 2022 Of particular importance, chronic ethanol feeding to C57BL/6 mice decreased the phosphorylation of apoptosis signal-regulating kinase 1 (ASK1) at serine (S)1036/S1040 (S1029/S1033 human), sites linked with the inhibition of ASK1 death-promoting activity. Ethanol 34-41 mitogen-activated protein kinase kinase kinase 5 Homo sapiens 224-228 35438255-7 2022 Of particular importance, chronic ethanol feeding to C57BL/6 mice decreased the phosphorylation of apoptosis signal-regulating kinase 1 (ASK1) at serine (S)1036/S1040 (S1029/S1033 human), sites linked with the inhibition of ASK1 death-promoting activity. Serine 146-152 mitogen-activated protein kinase kinase kinase 5 Mus musculus 99-135 35438255-7 2022 Of particular importance, chronic ethanol feeding to C57BL/6 mice decreased the phosphorylation of apoptosis signal-regulating kinase 1 (ASK1) at serine (S)1036/S1040 (S1029/S1033 human), sites linked with the inhibition of ASK1 death-promoting activity. Serine 146-152 mitogen-activated protein kinase kinase kinase 5 Mus musculus 137-141 35438255-9 2022 Decreased phosphorylation at S1033 was also lower in liver of patients with severe AH compared to healthy controls, and phosphorylation at the ASK1 activation site (threonine (Thr)-838) was increased in patients with AH. Threonine 165-174 mitogen-activated protein kinase kinase kinase 5 Homo sapiens 143-147 35438255-9 2022 Decreased phosphorylation at S1033 was also lower in liver of patients with severe AH compared to healthy controls, and phosphorylation at the ASK1 activation site (threonine (Thr)-838) was increased in patients with AH. Threonine 176-179 mitogen-activated protein kinase kinase kinase 5 Homo sapiens 143-147