PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35405526-0	2022	Metformin alleviates nickel-refining fumes-induced aerobic glycolysis via AMPK/GOLPH3 pathway in vitro and in vivo.	Metformin	0-9	protein kinase AMP-activated catalytic subunit alpha 2	Homo sapiens	74-78	
35405526-6	2022	Our findings indicated that Ni fumes expose evoked aerobic glycolysis by AMPK/GOLPH3, while metformin attenuated Ni particles-promoted GOLPH3-mediated aerobic glycolysis by p-AMPK expression increase.	Metformin	92-101	protein kinase AMP-activated catalytic subunit alpha 2	Homo sapiens	175-179	
35405526-11	2022	The results indicated that metformin decreased the protein levels of GOLPH3, LDHA, HK2, MCT-4 and improved p-AMPK expression.	Metformin	27-36	protein kinase AMP-activated catalytic subunit alpha 2	Homo sapiens	109-113	
35405526-12	2022	Thus, our findings demonstrated metformin antagonized Ni-refining fumes-caused aerobic glycolysis via AMPK/GOLPH3.	Metformin	32-41	protein kinase AMP-activated catalytic subunit alpha 2	Homo sapiens	102-106