PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35401236-0	2022	A Novel N-Arylpyridone Compound Alleviates the Inflammatory and Fibrotic Reaction of Silicosis by Inhibiting the ASK1-p38 Pathway and Regulating Macrophage Polarization.	n-arylpyridone	8-22	mitogen-activated protein kinase kinase kinase 5	Homo sapiens	113-117	
35401236-0	2022	A Novel N-Arylpyridone Compound Alleviates the Inflammatory and Fibrotic Reaction of Silicosis by Inhibiting the ASK1-p38 Pathway and Regulating Macrophage Polarization.	n-arylpyridone	8-22	mitogen-activated protein kinase 14	Homo sapiens	118-121	
35401236-4	2022	In vivo, our results showed that AKEX0011 ameliorated silica-induced imaging lung damages, respiratory dysfunction, reduced the secretion of inflammatory and fibrotic factors (TNF-alpha, IL-1beta, IL-6, TGF-beta, IL-4, and IL-10), and the deposition of fibrosis-related proteins (collagen I, fibronectin, and alpha-SMA), regardless of early or advanced therapy.	Silicon Dioxide	54-60	tumor necrosis factor	Homo sapiens	176-185	
35401236-4	2022	In vivo, our results showed that AKEX0011 ameliorated silica-induced imaging lung damages, respiratory dysfunction, reduced the secretion of inflammatory and fibrotic factors (TNF-alpha, IL-1beta, IL-6, TGF-beta, IL-4, and IL-10), and the deposition of fibrosis-related proteins (collagen I, fibronectin, and alpha-SMA), regardless of early or advanced therapy.	Silicon Dioxide	54-60	interleukin 1 alpha	Homo sapiens	187-195	
35401236-4	2022	In vivo, our results showed that AKEX0011 ameliorated silica-induced imaging lung damages, respiratory dysfunction, reduced the secretion of inflammatory and fibrotic factors (TNF-alpha, IL-1beta, IL-6, TGF-beta, IL-4, and IL-10), and the deposition of fibrosis-related proteins (collagen I, fibronectin, and alpha-SMA), regardless of early or advanced therapy.	Silicon Dioxide	54-60	interleukin 6	Homo sapiens	197-201	
35401236-4	2022	In vivo, our results showed that AKEX0011 ameliorated silica-induced imaging lung damages, respiratory dysfunction, reduced the secretion of inflammatory and fibrotic factors (TNF-alpha, IL-1beta, IL-6, TGF-beta, IL-4, and IL-10), and the deposition of fibrosis-related proteins (collagen I, fibronectin, and alpha-SMA), regardless of early or advanced therapy.	Silicon Dioxide	54-60	transforming growth factor alpha	Homo sapiens	203-211	
35401236-4	2022	In vivo, our results showed that AKEX0011 ameliorated silica-induced imaging lung damages, respiratory dysfunction, reduced the secretion of inflammatory and fibrotic factors (TNF-alpha, IL-1beta, IL-6, TGF-beta, IL-4, and IL-10), and the deposition of fibrosis-related proteins (collagen I, fibronectin, and alpha-SMA), regardless of early or advanced therapy.	Silicon Dioxide	54-60	interleukin 4	Homo sapiens	213-217	
35401236-4	2022	In vivo, our results showed that AKEX0011 ameliorated silica-induced imaging lung damages, respiratory dysfunction, reduced the secretion of inflammatory and fibrotic factors (TNF-alpha, IL-1beta, IL-6, TGF-beta, IL-4, and IL-10), and the deposition of fibrosis-related proteins (collagen I, fibronectin, and alpha-SMA), regardless of early or advanced therapy.	Silicon Dioxide	54-60	interleukin 10	Homo sapiens	223-228	
35401236-4	2022	In vivo, our results showed that AKEX0011 ameliorated silica-induced imaging lung damages, respiratory dysfunction, reduced the secretion of inflammatory and fibrotic factors (TNF-alpha, IL-1beta, IL-6, TGF-beta, IL-4, and IL-10), and the deposition of fibrosis-related proteins (collagen I, fibronectin, and alpha-SMA), regardless of early or advanced therapy.	Silicon Dioxide	54-60	fibronectin 1	Homo sapiens	292-303	
35401236-4	2022	In vivo, our results showed that AKEX0011 ameliorated silica-induced imaging lung damages, respiratory dysfunction, reduced the secretion of inflammatory and fibrotic factors (TNF-alpha, IL-1beta, IL-6, TGF-beta, IL-4, and IL-10), and the deposition of fibrosis-related proteins (collagen I, fibronectin, and alpha-SMA), regardless of early or advanced therapy.	Silicon Dioxide	54-60	actin alpha 1, skeletal muscle	Homo sapiens	309-318