PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35395477-0	2022	Ultrasound-triggered reactive oxygen species effector nanoamplifier for enhanced combination therapy of mutant p53 tumors.	Reactive Oxygen Species	21-44	tumor protein p53	Homo sapiens	111-114	
35395477-2	2022	In this study, we built an ultrasound-triggered ROS damage nanoamplifier using a synergistic strategy consisting of ROS damage and decreased tumor self-protection capability to enhance the treatment efficacy of mutant p53 tumors.	Reactive Oxygen Species	48-51	tumor protein p53	Homo sapiens	218-221	
35395477-2	2022	In this study, we built an ultrasound-triggered ROS damage nanoamplifier using a synergistic strategy consisting of ROS damage and decreased tumor self-protection capability to enhance the treatment efficacy of mutant p53 tumors.	Reactive Oxygen Species	116-119	tumor protein p53	Homo sapiens	218-221	
35395477-5	2022	In addition, TH287 allies with ROS to eliminate the mutated p53 protein in tumor cells, thus reducing the self-protective capacity of tumor cells.	Reactive Oxygen Species	31-34	tumor protein p53	Homo sapiens	60-63	
35395477-7	2022	The construction of a ROS nanoamplifier not only provides an effective strategy for the treatment of mutant p53 tumors but also supplies an integrated platform for tumor diagnosis and therapy.	Reactive Oxygen Species	22-25	tumor protein p53	Homo sapiens	108-111