PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35366770-5 2022 This P450c17 cytochrome gene is a critical steroidogenesis regulator which performs two distinct activities: 17 alpha-hydroxylase activity (converting pregnenolone to 17-hydroxypregnenolone and progesterone to 17-hydroxyprogesterone, these precursors are further processed to provide glucocorticoids and sex hormones) and 17, 20-lyase activity (which converts 17-hydroxypregnenolone to DHEA). Dehydroepiandrosterone 386-390 cytochrome P450 family 17 subfamily A member 1 Homo sapiens 5-12