PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35362831-0	2022	Bone tissue engineering using 3D silk scaffolds and human dental pulp stromal cells epigenetic reprogrammed with the selective histone deacetylase inhibitor MI192.	MI-192	157-162	histone deacetylase 9	Homo sapiens	127-146	
35362831-3	2022	This study investigated the potential of using a selective HDAC2 and 3 inhibitor, MI192, to promote human dental pulp stromal cells (hDPSCs) bone-like tissue formation in vitro and in vivo within porous Bombyx Mori silk scaffolds.	MI-192	82-87	histone deacetylase 2	Homo sapiens	59-70	
35362831-6	2022	MI192 pre-treatment of hDPSCs on 5 wt% silk scaffold significantly enhanced hDPSCs alkaline phosphatase activity (ALP).	MI-192	0-5	alkaline phosphatase, placental	Homo sapiens	114-117	
35362831-7	2022	The expression of osteoblast-related genes (RUNX2, ALP, Col1a, OCN) was significantly upregulated in the MI192 pre-treated cells.	MI-192	105-110	RUNX family transcription factor 2	Homo sapiens	44-49	
35362831-7	2022	The expression of osteoblast-related genes (RUNX2, ALP, Col1a, OCN) was significantly upregulated in the MI192 pre-treated cells.	MI-192	105-110	alkaline phosphatase, placental	Homo sapiens	51-54	
35362831-7	2022	The expression of osteoblast-related genes (RUNX2, ALP, Col1a, OCN) was significantly upregulated in the MI192 pre-treated cells.	MI-192	105-110	bone gamma-carboxyglutamate protein	Homo sapiens	63-66	
35362831-8	2022	Histological analysis confirmed that the MI192 pre-treated hDPSCs-silk scaffold constructs promoted bone extracellular matrix (ALP, Col1a, OCN) deposition and mineralisation compared to the untreated group.	MI-192	41-46	alkaline phosphatase, placental	Homo sapiens	127-130	
35362831-8	2022	Histological analysis confirmed that the MI192 pre-treated hDPSCs-silk scaffold constructs promoted bone extracellular matrix (ALP, Col1a, OCN) deposition and mineralisation compared to the untreated group.	MI-192	41-46	bone gamma-carboxyglutamate protein	Homo sapiens	139-142