PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35301287-0 2022 Claudin1 decrease induced by 1,25-dihydroxy-vitamin D3 potentiates gefitinib resistance therapy through inhibiting AKT activation-mediated cancer stem-like properties in NSCLC cells. Gefitinib 67-76 AKT serine/threonine kinase 1 Homo sapiens 115-118 35301287-8 2022 Collectively, inhibition of claudin1-mediated cancer stem-like properties by 1,25(OH)2D3 may decrease gefitinib resistance through the AKT pathway, which may be a promising therapeutic strategy for inhibiting gefitinib resistance in EGFR-mutant lung adenocarcinoma. Gefitinib 102-111 AKT serine/threonine kinase 1 Homo sapiens 135-138 35301287-8 2022 Collectively, inhibition of claudin1-mediated cancer stem-like properties by 1,25(OH)2D3 may decrease gefitinib resistance through the AKT pathway, which may be a promising therapeutic strategy for inhibiting gefitinib resistance in EGFR-mutant lung adenocarcinoma. Gefitinib 209-218 AKT serine/threonine kinase 1 Homo sapiens 135-138