PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35264503-8 2022 Along with the activated STAT5 pathway, a common feature across all AEL cases, these AEL cases exhibited enhanced cell proliferation and heme metabolism, and they showed high sensitivity to ruxolitinib in in vitro and in xenograft models, highlighting the potential role of JAK2 inhibition in AEL therapeutics. ruxolitinib 190-201 signal transducer and activator of transcription 5A Homo sapiens 25-30 35264503-8 2022 Along with the activated STAT5 pathway, a common feature across all AEL cases, these AEL cases exhibited enhanced cell proliferation and heme metabolism, and they showed high sensitivity to ruxolitinib in in vitro and in xenograft models, highlighting the potential role of JAK2 inhibition in AEL therapeutics. ruxolitinib 190-201 Janus kinase 2 Homo sapiens 274-278