PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35222283-0 2022 Metformin Downregulates the Expression of Epidermal Growth Factor Receptor Independent of Lowering Blood Glucose in Oral Squamous Cell Carcinoma. Metformin 0-9 epidermal growth factor receptor Homo sapiens 42-74 35222283-5 2022 The patients were divided into groups according to whether they were taking metformin for the treatment of T2DM, and the expression of EGFR in different groups was compared. Metformin 76-85 epidermal growth factor receptor Homo sapiens 135-139 35222283-9 2022 Results: EGFR expression in T2DM patients with OSCC taking metformin was significantly lower than that in the non-metformin group. Metformin 59-68 epidermal growth factor receptor Homo sapiens 9-13 35222283-11 2022 In patients with recurrent OSCC with normal blood glucose, metformin remarkably reduced the expression of EGFR in recurrent OSCC tissues. Metformin 59-68 epidermal growth factor receptor Homo sapiens 106-110 35222283-12 2022 Conclusion: Metformin may regulate the expression of EGFR in a way that does not rely on lowering blood glucose. Metformin 12-21 epidermal growth factor receptor Homo sapiens 53-57