PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35218032-0	2022	Gamma-oryzanol protects human liver cell (L02) from hydrogen peroxide-induced oxidative damage through regulation of the MAPK/Nrf2 signaling pathways.	gamma-oryzanol	0-14	NFE2 like bZIP transcription factor 2	Homo sapiens	126-130	
35218032-6	2022	Furthermore, preincubation with Orz reduced H2 O2 -mediated the proapoptotic protein of Bak expression and the phosphorylation of ASK1, p38, JNK, and ERK, and increased the anti-apoptotic protein of Bcl-xl expression and anti-oxidative stress proteins of Nrf2 and HO-1 expression.	gamma-oryzanol	32-35	BCL2 antagonist/killer 1	Homo sapiens	88-91	
35218032-6	2022	Furthermore, preincubation with Orz reduced H2 O2 -mediated the proapoptotic protein of Bak expression and the phosphorylation of ASK1, p38, JNK, and ERK, and increased the anti-apoptotic protein of Bcl-xl expression and anti-oxidative stress proteins of Nrf2 and HO-1 expression.	gamma-oryzanol	32-35	mitogen-activated protein kinase kinase kinase 5	Homo sapiens	130-134	
35218032-6	2022	Furthermore, preincubation with Orz reduced H2 O2 -mediated the proapoptotic protein of Bak expression and the phosphorylation of ASK1, p38, JNK, and ERK, and increased the anti-apoptotic protein of Bcl-xl expression and anti-oxidative stress proteins of Nrf2 and HO-1 expression.	gamma-oryzanol	32-35	mitogen-activated protein kinase 14	Homo sapiens	136-139	
35218032-6	2022	Furthermore, preincubation with Orz reduced H2 O2 -mediated the proapoptotic protein of Bak expression and the phosphorylation of ASK1, p38, JNK, and ERK, and increased the anti-apoptotic protein of Bcl-xl expression and anti-oxidative stress proteins of Nrf2 and HO-1 expression.	gamma-oryzanol	32-35	mitogen-activated protein kinase 8	Homo sapiens	141-144	
35218032-6	2022	Furthermore, preincubation with Orz reduced H2 O2 -mediated the proapoptotic protein of Bak expression and the phosphorylation of ASK1, p38, JNK, and ERK, and increased the anti-apoptotic protein of Bcl-xl expression and anti-oxidative stress proteins of Nrf2 and HO-1 expression.	gamma-oryzanol	32-35	mitogen-activated protein kinase 1	Homo sapiens	150-153	
35218032-6	2022	Furthermore, preincubation with Orz reduced H2 O2 -mediated the proapoptotic protein of Bak expression and the phosphorylation of ASK1, p38, JNK, and ERK, and increased the anti-apoptotic protein of Bcl-xl expression and anti-oxidative stress proteins of Nrf2 and HO-1 expression.	gamma-oryzanol	32-35	BCL2 like 1	Homo sapiens	199-205	
35218032-6	2022	Furthermore, preincubation with Orz reduced H2 O2 -mediated the proapoptotic protein of Bak expression and the phosphorylation of ASK1, p38, JNK, and ERK, and increased the anti-apoptotic protein of Bcl-xl expression and anti-oxidative stress proteins of Nrf2 and HO-1 expression.	gamma-oryzanol	32-35	NFE2 like bZIP transcription factor 2	Homo sapiens	255-259	
35218032-6	2022	Furthermore, preincubation with Orz reduced H2 O2 -mediated the proapoptotic protein of Bak expression and the phosphorylation of ASK1, p38, JNK, and ERK, and increased the anti-apoptotic protein of Bcl-xl expression and anti-oxidative stress proteins of Nrf2 and HO-1 expression.	gamma-oryzanol	32-35	heme oxygenase 1	Homo sapiens	264-268	
35218032-6	2022	Furthermore, preincubation with Orz reduced H2 O2 -mediated the proapoptotic protein of Bak expression and the phosphorylation of ASK1, p38, JNK, and ERK, and increased the anti-apoptotic protein of Bcl-xl expression and anti-oxidative stress proteins of Nrf2 and HO-1 expression.	Hydrogen Peroxide	44-49	BCL2 antagonist/killer 1	Homo sapiens	88-91	
35218032-6	2022	Furthermore, preincubation with Orz reduced H2 O2 -mediated the proapoptotic protein of Bak expression and the phosphorylation of ASK1, p38, JNK, and ERK, and increased the anti-apoptotic protein of Bcl-xl expression and anti-oxidative stress proteins of Nrf2 and HO-1 expression.	Hydrogen Peroxide	44-49	mitogen-activated protein kinase kinase kinase 5	Homo sapiens	130-134	
35218032-6	2022	Furthermore, preincubation with Orz reduced H2 O2 -mediated the proapoptotic protein of Bak expression and the phosphorylation of ASK1, p38, JNK, and ERK, and increased the anti-apoptotic protein of Bcl-xl expression and anti-oxidative stress proteins of Nrf2 and HO-1 expression.	Hydrogen Peroxide	44-49	mitogen-activated protein kinase 14	Homo sapiens	136-139	
35218032-6	2022	Furthermore, preincubation with Orz reduced H2 O2 -mediated the proapoptotic protein of Bak expression and the phosphorylation of ASK1, p38, JNK, and ERK, and increased the anti-apoptotic protein of Bcl-xl expression and anti-oxidative stress proteins of Nrf2 and HO-1 expression.	Hydrogen Peroxide	44-49	mitogen-activated protein kinase 8	Homo sapiens	141-144	
35218032-6	2022	Furthermore, preincubation with Orz reduced H2 O2 -mediated the proapoptotic protein of Bak expression and the phosphorylation of ASK1, p38, JNK, and ERK, and increased the anti-apoptotic protein of Bcl-xl expression and anti-oxidative stress proteins of Nrf2 and HO-1 expression.	Hydrogen Peroxide	44-49	mitogen-activated protein kinase 1	Homo sapiens	150-153	
35218032-6	2022	Furthermore, preincubation with Orz reduced H2 O2 -mediated the proapoptotic protein of Bak expression and the phosphorylation of ASK1, p38, JNK, and ERK, and increased the anti-apoptotic protein of Bcl-xl expression and anti-oxidative stress proteins of Nrf2 and HO-1 expression.	Hydrogen Peroxide	44-49	BCL2 like 1	Homo sapiens	199-205	
35218032-6	2022	Furthermore, preincubation with Orz reduced H2 O2 -mediated the proapoptotic protein of Bak expression and the phosphorylation of ASK1, p38, JNK, and ERK, and increased the anti-apoptotic protein of Bcl-xl expression and anti-oxidative stress proteins of Nrf2 and HO-1 expression.	Hydrogen Peroxide	44-49	NFE2 like bZIP transcription factor 2	Homo sapiens	255-259	
35218032-6	2022	Furthermore, preincubation with Orz reduced H2 O2 -mediated the proapoptotic protein of Bak expression and the phosphorylation of ASK1, p38, JNK, and ERK, and increased the anti-apoptotic protein of Bcl-xl expression and anti-oxidative stress proteins of Nrf2 and HO-1 expression.	Hydrogen Peroxide	44-49	heme oxygenase 1	Homo sapiens	264-268	
35218032-7	2022	The findings suggested that Orz exerts the cytoprotective effects in H2 O2 -induced L02 cells apoptosis by ameliorating oxidative stress via inhibiting MAPK signaling pathway and activating Nrf2 signaling pathway.	gamma-oryzanol	28-31	NFE2 like bZIP transcription factor 2	Homo sapiens	190-194	
35218032-7	2022	The findings suggested that Orz exerts the cytoprotective effects in H2 O2 -induced L02 cells apoptosis by ameliorating oxidative stress via inhibiting MAPK signaling pathway and activating Nrf2 signaling pathway.	Hydrogen Peroxide	69-74	NFE2 like bZIP transcription factor 2	Homo sapiens	190-194	
35218032-9	2022	In this study, it was found that Orz exerts the cytoprotective effects in H2 O2 -induced L02 cell apoptosis by ameliorating oxidative stress via the inhibition of MAPK signaling pathway and the activation of Nrf2 signaling pathway, which provides a theoretical basis for dietary adding natural products to prevent or treat oxidative stress-related diseases.	gamma-oryzanol	33-36	NFE2 like bZIP transcription factor 2	Homo sapiens	208-212