PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35217685-3 2022 Here we identify DAGLB (diacylglycerol lipase-beta), a key enzyme for generation of the endocannabinoid 2-AG (2-arachidonoylglycerol), as a cargo of AP-4 vesicles. glyceryl 2-arachidonate 104-108 transcription factor AP-4 Homo sapiens 149-153 35217685-3 2022 Here we identify DAGLB (diacylglycerol lipase-beta), a key enzyme for generation of the endocannabinoid 2-AG (2-arachidonoylglycerol), as a cargo of AP-4 vesicles. glyceryl 2-arachidonate 110-132 transcription factor AP-4 Homo sapiens 149-153 35217685-5 2022 We show that DAGLB accumulates at the trans-Golgi network of AP-4-deficient cells, that axonal DAGLB levels are reduced in neurons from a patient with AP-4 deficiency, and that 2-AG levels are reduced in the brains of AP-4 knockout mice. glyceryl 2-arachidonate 177-181 transcription factor AP-4 Homo sapiens 61-65 35217685-5 2022 We show that DAGLB accumulates at the trans-Golgi network of AP-4-deficient cells, that axonal DAGLB levels are reduced in neurons from a patient with AP-4 deficiency, and that 2-AG levels are reduced in the brains of AP-4 knockout mice. glyceryl 2-arachidonate 177-181 transcription factor AP-4 Homo sapiens 218-222