PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35154486-0 2022 Overexpression of MFN2 alleviates sorafenib-induced cardiomyocyte necroptosis via the MAM-CaMKIIdelta pathway in vitro and in vivo. 6-O-monoacetylmorphine 86-89 mitofusin 2 Mus musculus 18-22 35154486-14 2022 In an in vivo model, mice subjected to sor administration developed cardiac dysfunction, autophagy activation and necroptosis; our investigation found that global and cardiac-specific overexpression of MFN2 repressed cardiac dysfunction, and sor-induced cardiomyocyte necroptosis via repressing the MAM-CaMKIIdelta-RIP3/MLKL pathway. 6-O-monoacetylmorphine 299-302 mitofusin 2 Mus musculus 202-206