PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 35116094-0 2022 Liensinine Inhibits Osteosarcoma Growth by ROS-Mediated Suppression of the JAK2/STAT3 Signaling Pathway. Reactive Oxygen Species 43-46 signal transducer and activator of transcription 3 Mus musculus 80-85 35116094-12 2022 Additionally, liensinine promoted intracellular ROS production, enhanced the GSSG/GSH ratio, and induced MMP loss and ROS-mediated suppression of the JAK2/STAT3 pathway. Reactive Oxygen Species 118-121 signal transducer and activator of transcription 3 Mus musculus 155-160 35116094-15 2022 In conclusion, liensinine-induced ROS production could suppress the activation of the JAK2/STAT3 pathway and inhibit the OS growth both in vivo and in vitro. Reactive Oxygen Species 34-37 signal transducer and activator of transcription 3 Mus musculus 91-96